Vaidyanathan,  —

Fabry disease is a rare genetic disease that results from abnormal buildup of a type of fat called globotriaosylceramide (Gb3 or GL-3) inside cells and tissues. Gb3 accumulation can cause a wide range of symptoms, which can pose problems for travelers who have the disease. Here are some tips…

Fabry disease is a rare genetic disease in which mutations in the GLA gene lead to the accumulation of a type of fat called globotriaosylceramide (Gb3 or GL-3) in cells and tissues. Fabry disease affects multiple organs, and many patients experience Fabry crises, intense episodes…

Fabry disease is a rare genetic disorder characterized by the accumulation of a type of fat called globotriaosylceramide (Gb3 or GL-3) inside cells. Its symptoms, such as muscle weakness, kidney dysfunction, heart disease, Fabry crises, and various skin and eye problems, can be quite…

Fabry disease is a lysosomal storage disorder caused by mutations in the GLA gene. These mutations result in deficient amounts of an enzyme called alpha-galactosidase A being produced that, in turn, causes a type of fat called globotriaosylceramide (Gb3 or GL-3) to accumulate inside cells. An…

Fabry disease is a rare genetic disease that occurs as a result of a mutation in the GLA gene. This leads to a deficiency in the production of an enzyme called alpha-galactosidase A, due to the accumulation of a type of fat called globotriaosylceramide (Gb3 or GL-3) in…

Enzyme replacement therapy (ERT), such as Fabrazyme, addresses the primary cause of Fabry disease — mutations in the GLA gene that lead to the lack of alpha-galactosidase A enzyme, which is needed to break down a type of fat called globotriaosylceramide (Gb3 or GL-3). A deficiency…

Heart disease is common in Fabry disease patients, and those with the disease should be vigilant about taking steps to optimize their cardiac care. Fabry disease…

Kidney problems are common in people with Fabry disease. They are caused by the deposition of certain fatty molecules, known as globotriaosylceramide (Gb3 or GL-3), that accumulate inside cells due to a lack of the enzyme alpha-galactosidase A. If not attended to, kidney problems can progress to kidney failure.

Fabry disease is a rare X-linked genetic disorder characterized by the inability of the body to break down a type of fat called globotriaosylceramide (Gb3 or GL-3) due to deficiency of the alpha-galactosidase A enzyme. Sweating abnormalities such as anhidrosis (decreased sweating) and hyperhidrosis…

Fabry disease is a rare X-linked genetic disease characterized by the buildup of a type of fat called globotriaosylceramide (Gb3 or GL-3) inside cells, resulting in a variety of symptoms that can be life-threatening. Fabry disease patients often experience gastrointestinal (GI) symptoms such as cramps in…