Jonathan Grinstein,  —

Objective Cognitive Impairment Linked to Sex, Stroke, and IQ, Study Shows

Male sex, history of stroke, and intelligence quotient (IQ) are associated with an increased risk of objective cognitive impairment in Fabry disease patients. Depressive symptoms, on the other hand, are related to increased subjective cognitive complaints, a study found. The study, “Predictors of objective cognitive impairment and subjective…

Avrobio Earns FDA Orphan Drug Designation for Fabry Treatment AVR-RD-01

The U.S. Food And Drug Administration (FDA) has granted orphan drug status to Avrobio’s investigational gene therapy AVR-RD-01 for the treatment of Fabry disease. AVR-RD-01 is being tested in two separate clinical trials that are still recruiting patients: AVRO-RD-01-201 Phase 2 trial (NCT03454893) and an investigator-sponsored Phase…